Microfl09block2.1_1 - Microbial Interactions physical...

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5/10/10 Microbial Interactions physical interaction with other organisms - ectosymbiont, endosymbiont mutualism - reciprocal benefit between both partners, obligatory cooperation - positive interaction for both organisms, not obligatory commensalism - one benefits, the
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5/10/10 Human Microbe Interactions
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5/10/10 Indigenous Microbes normal microbial flora - microbes normally associated with the human body surface tissues (skin, mucous membranes, etc.) are readily colonized lumenal surfaces importance of understanding of
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5/10/10 Skin 1012 bacteria on normal human skin resident or transient - resident - normally grow in skin - transient - Mouth organism must be able to colonize the mouth by attachment to gums and teeth Streptococcus mutans and parasanguis -
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5/10/10 Pathogenesis Pathogen – any agent that causes disease Pathogenicity – the ability to cause disease by overcoming the hosts defenses Infection – growth of a parasite within a host Virulence – the quantitative measure
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5/10/10 Bacterial Pathogenesis 1. Maintain a reservoir - other humans or another animal 2. Transport and entry to host - direct contact: host to host, contact with fomites, arthropod vectors 3. Adhere, colonize/invade host cells or
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Microfl09block2.1_1 - Microbial Interactions physical...

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