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Lecture3_30 - Chapter 20 Protein Structure Sequence of...

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3/28/2010 1 Chapter 20 Protein Structure Sequence of Amino Acids Regular repeating ordered spatial arrangements of amino acids, which result from hydrogen bonds between carbonyl oxygen and amino hydrogen atoms Overall 3-D Structure 3-D structure of a protein consisting of two or more independent peptide chains
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3/28/2010 2 Three types of proteins: Fibrous, Globular Membrane Fibrous proteins: protein molecules with elongated shape with one dimension much longer than the others Generally insoluble in water Single type of secondary structure Tend to have simple, regular, linear structures. Tend to aggregate together to form macromolecular structures, e.g., hair, nails, etc. Globular proteins: protein molecules with peptide chains folded into spherical or globular shapes: Generally water soluble hydrophobic amino acid residues are in the protein core, while hydrophilic amino acids are on the outside of the molecule.
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