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Unformatted text preview: Replicating the Ends of DNA Molecules Lagging Strand has no 3 end for DNA Pol once primer is removed In second round of replication both strands are shortened Telomeres Repetitive DNA sequence at the ends TTAGGG (110-1000 times) Help protect DNA from systems that monitor DNA damage stop division or cell death Packaging of DNA Histone Proteins H2A H2B H3 H4 Positively Charged (bind to negatively charged DNA molecule) Nucleosome DNA wound twice a protein core of 2 each of the histones Linker DNA 30 nm Fiber Interaction between histone tails and linker DNA Typical of Interphase Looped Domains Attached to Chromosome Scaffolding (proteins) Topoisomerase, Histone 1 present Chromosome Euchromatin Heterochromatin- visable not available for activity...
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