Review of Monohybrid Crosses %26 Probability

Genetics: A Conceptual Approach

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Unformatted text preview: Mendel’s Principle of Segregation states that… …each individual diploid organism possesses two alleles for any particular characteristic Aa Mendel’s Principle of Segregation states that… …each individual diploid organism possesses two alleles for any particular characteristic …these two alleles segregate (separate) when gametes are formed, and one allele goes into each gamete Aa A a Mendel’s Principle of Segregation states that… …each individual diploid organism possesses two alleles for any particular characteristic …these two alleles segregate (separate) when gametes are formed, and one allele goes into each gamete …the two alleles segregate into gametes in equal proportions Aa A a ½ A ½ a (2n) Mendel’s Principle of Segregation Is Due to Separation of Homologous Chromosomes During Meiosis A A a a A A a a A A a a Metaphase I End of Meiosis I End of Meiosis II Aa ½ A ½ a gametes (n) Working Crosses Step 1 : Write out the cross Step 2: Determine the gametes produced by each parent Step 3: Determine all fertilization combinations (which define the genotypes and phenotypes of offspring) Working Crosses Cystic fibrosis is caused by a recessive allele ( d ). Individuals that possess at least one normal allele ( D ) are unaffected by the disease. If Bob and Nancy are both heterozygous, what is the expected genotypic & phenotypic ratio of their children? Step 1 : Write out the cross D = unaffected d = affected (cystic fibrosis) D > d Cystic fibrosis is caused by a recessive allele (...
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This note was uploaded on 05/06/2010 for the course BIO 311 taught by Professor Otto during the Spring '10 term at George Mason.

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Review of Monohybrid Crosses %26 Probability - Mendel’s...

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