Chapters 1 & 2_post

Genetics: A Conceptual Approach

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Chapter 1 (Introduction) Dr. Ed Otto George Mason University
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The Science of Genetics Genetics is the science of heredity and variation in living organisms It is divided into 3 major subdisciplines 1.Transmission genetics 2. Molecular genetics 3. Population genetics
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Transmission Genetics Transmission Genetics: Encompasses basic principles of genetics and how traits are passed from one generation to the next Focus is on the individual organism– how the individual organism inherits its genetic makeup and passes its genes to the next generation
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Molecular Genetics Molecular Genetics: Concerns the chemical nature of the gene: how genetic information is encoded, replicated and expressed Focus is on the gene– its structure, organization, and function
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Population Genetics Population Genetics: Explores the genetic composition of groups of individuals (populations) and how composition changes over time and geographic space Focus is on gene pool
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So why is genetics important to you?
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Some Reasons Why Genetics May Be Important To You Genetics provides one of biology’s unifying principles: all organisms use genetic systems that have a number of features in common Genetic principles underlie many other biological disciplines. For example: Evolution is genetic change over time, so the study of evolution requires an understanding of genetics Developmental biology relies heavily on the use of genetics: tissues and organs form through the regulated expression of genes As a biologist:
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Molecular genetics is the basis for medical biotechnology Drugs and Vaccines: Many leading drugs and vaccines are produced using recombinant DNA technologies - Examples : insulin, Gardasil® (new HPV vaccine), clotting factors for hemophilia As a future medical professional or consumer: Some Reasons Why Genetics May Be Important To You
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Some Reasons Why This Course Should Be Important To You Gene therapies Treating patient with genes rather than drugs Unlike drug, gene transfer may provide prolonged benefit to patient Genetic testing and counseling Increasing availability of tests for genetic diseases Principles of transmission genetics used to counsel couples on probabilities that a child born to them will be affected with genetic disease As a future medical professional or consumer:
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Some Reasons Why This Course Should Be Important To You Personalized medicine Use of patient’s genetic information to guide treatment (e.g. Herceptin® prescribed only for patients with breast tumors with specific genetic makeup) As a future medical professional or consumer:
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Some Reasons Why This Course Should Be Important To You Agricultural applications Improved crop yields achieved through traditional genetic breeding methods and biotechnology Crops with improved nutritional value Industrial applications Use biotechnology to produce biofuels, industrial enzymes Ethical issues Privacy rights for genetic information As scientist, consumer, or citizen:
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Chapter 2 Chromosomes and Cellular Reproduction
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Chapters 1 & 2_post - Chapter 1 (Introduction) Dr....

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