Additional slides from lecture 1

Genetics: A Conceptual Approach

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Hemophilia B Hemophilia B is an inherited bleeding disorder Individuals with this disease fail to produce a blood clotting protein Risks associated with the disease : - Scarring of the joints - Vision loss from bleeding into the eye - Chronic anemia from blood loss. - Death, which may occur with large amounts of blood loss or bleeding in critical areas, such as the brain.
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Treatment for the disease When bleeding episodes occur, patients are given clotting protein (isolated from the blood of individuals without hemophilia) Concentration of clotting protein in blood of unaffected individuals is low, so clotting protein for therapy had to be isolated from large pool of blood donated by many people. 10,000 units of blood pooled Single batch of “Blood-derived” clotting protein Many blood donors Hemophilia patients
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Devastating effects of HIV/AIDS From the late 1970s to the mid-1980s, about half of all people with hemophilia became infected with HIV through blood products.
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This note was uploaded on 05/06/2010 for the course BIO 311 taught by Professor Otto during the Spring '10 term at George Mason.

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Additional slides from lecture 1 - Hemophilia B Hemophilia...

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