Additional slides for lecture 3

Genetics: A Conceptual Approach

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a. Give the genotypes of Lucy, her brother, her mother, and her father Adenosine deaminase deficiency is an inherited disease in which affected persons are immune compromised. This disease results from an allele (a) that is recessive to the allele for normal immune function (A). Lucy has normal immune function, but her brother has the disorder. Lucy’s mother has the disorder, and her father is unaffected.
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a. Give the genotypes of Lucy, her brother, her mother, and her father Adenosine deaminase deficiency is an inherited disease in which affected persons are immune compromised. This disease results from an allele (a) that is recessive to the allele for normal immune function (A). Lucy has normal immune function, but her brother has the disorder. Lucy’s mother has the disorder, and her father is unaffected. P mother X father (affected) (unaffected) Write down info given in problem F 1 brother Lucy (affected) (unaffected)
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a. Give the genotypes of Lucy, her brother, her mother, and her father Adenosine deaminase deficiency is an inherited disease in which affected persons are immune compromised. This disease results from an allele (a) that is recessive to the allele for normal immune function (A). Lucy has normal immune function, but her brother has the disorder. Lucy’s mother has the disorder, and her father is unaffected. Assign obvious genotypes P mother X father (affected) (unaffected) aa F 1 brother Lucy (affected) (unaffected) aa Must be aa since disease is recessive
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a. Give the genotypes of Lucy, her brother, her mother, and her father Adenosine deaminase deficiency is an inherited disease in which affected persons are immune compromised. This disease results from an allele (a) that is recessive to the allele for normal immune function (A). Lucy has normal immune function, but her brother has the disorder. Lucy’s mother has the disorder, and her father is unaffected. Assign obvious genotypes P mother X father (affected) (unaffected) aa A_ F 1 brother Lucy (affected) (unaffected) aa A_ Must be aa since disease is recessive Must have at least one A allele since unaffected
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a. Give the genotypes of Lucy, her brother, her mother, and her father Adenosine deaminase deficiency is an inherited disease in which affected persons are immune compromised. This disease results from an allele (a) that is recessive to the allele for normal immune function (A). Lucy has normal immune function, but her brother has the disorder. Lucy’s mother has the disorder, and her father is unaffected. Assign inferred genotypes P mother X father (affected) (unaffected) aa A_ F 1 brother Lucy (affected) (unaffected) aa A_ Since brother is aa, must have inherited a allele from father and from mother (i.e. father must possess a allele)
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a. Give the genotypes of Lucy, her brother, her mother, and her father Adenosine deaminase deficiency is an inherited disease in which affected persons are immune compromised. This disease results from an allele (a) that is recessive to the allele for normal immune function (A). Lucy has normal immune function, but her brother has the disorder.
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