Chapter 33 - Chapter 33 Supercritical-Fluid Chromatography

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Chapter 33 Supercritical-Fluid Chromatography Supercritical-fluid chromatography (SFC), in which the mobile phase is a supercritical fluid, is a hybrid of gas and liquid chromatography that combines some of the best features of each. For certain applications, it appears to be clearly superior to both gas-liquid and high- performance liquid chromatography.
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Important Properties of Supercritical Fluids A supercritical fluid is formed whenever a substance is heated above its critical temperature. At the critical temperature, a substance can no longer be condensed into its liquid state through the application of pressure. The physical properties of a substance in the supercritical-fluid state can be remarkably different from the same properties in either the liquid or the gaseous state.
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Instrumentation and Operating Variables Instruments for supercritical-fluid chromatography are similar in design to high-performance liquid chromatography. Columns
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Chapter 33 - Chapter 33 Supercritical-Fluid Chromatography

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