Unformatted text preview: Amino Acid Metabolism Problem Set Reading: Chapters 23 and 24 Problems: Chapter 23- 10, 11, 12, 13, 18 Then try these: 1. What is the function of leghemoglobin in plants with root noodles that contain nitrogen-fixing bacteria? Why is it not surprising that leghemoglobin has a structure similar to hemoglobin and myoglobin? 2. While the catabolic pathways differ, all 20 amino acids are converted to one of 7 metabolites: acetyl-CoA, acetoacetate, oxaloacetate, pyruvate, - ketogluterate, succinyl-CoA, or fumarate. What is the metabolic fate of each of these intermediates? 3. What are the sources of the 2 nitrogens and the carbon in urea? 4. Glyphosate, also known as Round-Up , is an herbicide that kills plants by inhibiting an enzyme in the amino acid biosynthetic pathway responsible for phenylalanine synthesis. Would it be safe to use glyphosate in areas where farm animals may accidentally eat plants that have been sprayed? Explain. 5. Individuals with type 1 albinism have a mutation in gene encoding the tyrosinase enzyme and thus cannot convert tyrosine to melanin precursors. Individuals with phenylketonuria (PKU) cannot synthesize tyrosine from phenylalanine, do they also suffer from albinism? Explain. ...
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- Spring '07