Lecture 14 cardiovascular 2 - Office Hours Lehman: TTh...

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1 Office Hours Lehman: TTh 10-11 am 5112 VLSB slehman Kaufer: M 12-1, F 9-10, F 10-11 5155A VLSB danielak Gross: W, Th 3-4 pm 5112 VLSB sgross
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2 Midterm 1 • Grades are now posted on bspace • Key is posted in glass case between 5108 and 5110 VLSB (to left of Lehman office) • Hours to see scantronsin 1018 VLSB: T & W 10-12
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3 Functions of Circulation • Supply O 2 and Nutrients • Remove ‘Wastes” • Temperature Regulation • Distribute hormones • Immuno-vigilance
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4 To perform these functions, the cardiovascular system needs to: • Maintain blood flow through lungs and tissues • Regulate distribution among tissues • Promote exchange: – of O2 and Co2 in lungs – nutrients and wastes in tissues – of heat in body core and extremities
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5 Figure 12-2 Recall: The heart pumps blood through systemic and pulmonary circuits Systemic circuits exchange nutrients, wastes, O 2 and CO 2 in tissues Pulmonary circuit exchanges O 2 and CO 2 in lungs
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6 The Heart produces pressure Note P Systemic Pressures that drives circulation
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7 The heart drives circulation by generating a pressure difference • The heart generates a hydrostatic pressure difference P • Flow rate is proportional to P: F = (1/R) P • Analogous to Ohm’s law I = (1/R)V V = IR • Resistance is determined by viscosity and by geometry of circulatory system (mostly by geometry -- the diameter of vessels)
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8 Figure 12-50 Analogy from the text: The heart develops a hydrostatic pressure ΔP that drives flows F i through different tissues, controlled by their resistances R i Δ P is ~ constant Distribution of flow is determined by resistances R i of different tissue beds F i = Δ P/R i
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This note was uploaded on 05/07/2010 for the course INTEG BIO 132 taught by Professor Lehman during the Spring '10 term at University of California, Berkeley.

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Lecture 14 cardiovascular 2 - Office Hours Lehman: TTh...

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