Lecture 16 Reproduction2

Lecture 16 Reproduction2 - Human Physiology IB132 Lecture...

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Lecture 26 Homeostasis of the Genome: the reproductive system Today: organ to organismal levels Human Physiology IB132
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Lecture Outline 1. Hormonal control of reproductive functions 2. Fertilization, pregnancy and childbirth Final Exam Information
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General pattern of hormonal control of reproductive function (male and female): Fig. 17-1 Gonadotropin- releasing Hormone Follicle- stimulating Hormone Luteinizing Hormone The brain controls reproduction, primarily using a feedback control system with 3 hormonal signals.
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Fig. 17.01
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Figure 17-6 Male reproductive system - anatomy Male accessory reproductive organs Scortum: cooler environment allowing spermatogenesis
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Figure 17-5 Testis - anatomy Figure 17-4 A cross-section of the seminiferous tubules
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Figure 17-4 A representative cross-section of the seminiferous tubules in the testis is sketched here. In response to FSH and testosterone, the Sertoli cells support spermatogenesis. In response to LH, the Leydig cells produce steroids, including testosterone.
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Sertoli cells support spermatogenesis in the seminiferous tubules in response to testosterone and FSH. Figure 17-9 Spermatogonia undergoing mitosis Primary spermatocytes Undergoing meiosis I Secondary spermatocytes undergoing meiosis II Spermatids differentiating Sperm Sertoli cell barrier: compartmentation
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Figure 17-7 Half of the spermatogonia do not differentiate 30-200 million sperm are produced per day. spermatogenesis
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Fig. 17-11 Hormonal control of reproductive function in males T is secreted in a pulsatile yet constant amount
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Fig. 17.03
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Transport of sperm Figure 17-10 Nitric oxide is an important vasodilator in this reflex. Sexual excitation Reflex pathway to penis engorgement ( erection ) Spinal reflex leads to Ejaculation ~ 3 ml of of semen (sperm + fluids) Containing 300 M sprems
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Sexual Function is Serious Business Sexual Function is Serious Business In the first week that Viagra was available in pharmacies in Canada (March 25 to 31, 1999), 20,600 prescriptions were filled. (Source: Pfizer Press Release)
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Viagra inhibits the enzyme PDE5 GC= guanilate cyclase
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Figure 17-13 Secondary oocytes are transported toward the uterus in the Fallopian tubes Female reproductive system - anatomy In women, oogenesis occurs in the ovaries
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Fig. 17.13b
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Human Anatomy on you tube! http://www.youtube.com/watch?v=5BWhx9oc8vE
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Lecture 16 Reproduction2 - Human Physiology IB132 Lecture...

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