Bordetella Pertussis

Bordetella Pertussis - Bordetella Pertussis Final Microbial...

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Bordetella Pertussis Final Microbial Paper Microbiology Section 01 Caitlin Berkefeld Overview Bordetella pertussis (B . Pertussis) is a small , coccobacillus . Coccobacillus are rod-shaped bacteria . Cocco comes from "cocci" meaning spherical shaped and bacillus comes from "bacilli" meaning elongated . B . pertussis , like most pathogenic bacteria , is Gram- negative . Gram-negative bacteria contain a lipopolysaccharide (LPS) layer . The LPS triggers the body's immune response. The immune system senses a cytokine reaction , which is toxic to the body. Because of this , the body initiates the inflammation of the tissues and blood vessels . B. pertussis is non-motile, meaning it doesn't move. Classification There are currently eight species in the Bordetella genus . Three species in this genus are known to be pathogenic to humans . B. pertussis and B. parapertussis are very similar species . Both species cause pertussis (whooping cough) in humans and are separated merely by the toxins they release during infection . B. parapertussis releases toxins that
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seem to cause a milder form of pertussis (whooping cough) . B . bronchiseptica causes respiratory disease in various mammals and occasionally in humans . The species is further separated from B. pertussis and B . parapertussis by being motile. The human pathology of the remaining five species is relatively unknown . B. avium and B. hinzii , are known to cause respiratory disease in poultry. Habitat B . pertussis colonize the cilia of the mammalian respiratory epithelium . The epithelium is a tissue composed of a layer of cells. The main purpose of the respiratory epithelium is to moisten and protect the airways . It was originally thought that B. pertussis did not invade
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This note was uploaded on 05/08/2010 for the course BIOL 350 taught by Professor Gus during the Spring '10 term at Montclair.

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Bordetella Pertussis - Bordetella Pertussis Final Microbial...

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