13. UTI Infections - Definitions Bacteriuria = bacteria in...

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Urinary Tract Infections (UTIs) Definitions • Bacteriuria = bacteria in the urine i) “Significant”: > 10 8 bacteria /L ii) “Asymptomatic”: significant bacteriuria in patient without symptoms Urinary tract infections may be uncomplicated (no other problems present) or complicated (caused by other factors and/or may cause permanent damage) Complicated UTIs • Associated with - anatomical disorder - neurological disorder - foreign body / stones • Disorders result in - obstruction -r e f l u x -s t a s i s • Can cause serious morbidity and mortality UTI Syndromes • Acute Cystitis - lower urinary tract infection • Acute Pyelonephritis - upper urinary tract infection - usually with cystitis • Recurrent UTI - relapse (20%) vs reinfection 80%) Epidemiology of UTIs • 1/3 to 1/2 of humans will have at least one serious UTI in their lifetime • most occur in otherwise healthy individuals • women are 30 - 40x more likely to have a serious UTI • 20 - 30% of women will have recurrent UTIs • prevalence is age and sex dependent Epidemiology of UTIs by Age Group Age Group Period Prevalence (%) (yr) Females Males <1 1 1 1 - 15 4 - 5 0.5 16 - 35 20 0.5 36 - 65 35 20 >65 40 35
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Risk Factors for UTIs Men • lack of circumcision • enlarged prostate • anal sex Women • short urethra
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This note was uploaded on 05/09/2010 for the course LMP 232 taught by Professor Crandall during the Spring '10 term at University of Toronto- Toronto.

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13. UTI Infections - Definitions Bacteriuria = bacteria in...

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