February 24, 2010
Nosocomial Methicillin-resistant Staphylococcus aureus in Elderly Populations
Microbial bacterial infections were once thought to be conquered with the advent of
antibiotics in the 1930’s.
Just three decades later antibiotic resistant microbial infections were
The first symptoms of methicillin-resistant Staphylococcus aureus (MRSA) was
documented in 1961 (Davis, Stewart, Crouch et al., 2004).
By 1968, the disease had its first
This virulent and potentially more dangerous form of Staphylococcal
aureus (S-aureus) infection is a serious concern in public health, and is a condition associated
with institutions (Davis et al., 2004; Klevens et al., 2007; Tacconelli, 2009; Skyman, Sjostrom,
& Hellstrom, 2010; Wise, 2007; Solberg, 2000; Huang, Cheung, Kaatz, & Ryback, 2010).
past 40 years MRSA has become a major problem throughout hospitals and health institutions
worldwide (Solberg, 2000).
MRSA infections now account for 20 to 40% of nosocomial S.
aureus infections in endemic hospitals internationally.
The quality of care delivered at hospitals
is now being associated with the number of MRSA infections developed during hospitalization
The pervasive and potentially mortal nature of the spread of MRSA has the
medical field up-in-arms to fight the spread of this infection.
Antibiotic resistant bacterial infections create additional complications in treating injuries
With the increased prevalence of resistant S. aureus, recovering from surgery,
treating open wounds, and mitigating the risk of infection is once again a serious challenge in
treating patients (Wise, 2007).
While Methicillin-susceptible Staphylococcus aureus (MSSA)
was once easily treated by taking an oral regimen of amoxicillin, ampicillin or other commonly
prescribed antibiotic for infections on the skin, in soft-tissue, or in open wounds, with the
occasional use of intravenous delivery of an antibiotic for internal organs or advanced infections.