lecture 16

lecture 16 - Lecture 16(Chapter 10 Foodborne and Waterborne...

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1 Lecture 16 (Chapter 10) Foodborne and Waterborne Bacterial Diseases. A. Foodborne and Waterborne Intoxications. 1. ! Botulism 2. ! Staphylococcal food poisoning 3. ! Clostridial food poisoning 4. ! Bacillus cereus food poisoning B. Foodborne and Waterborne Infections 1. Typhoid fever 2. Salmonellosis 3. Shigellosis 4. Cholera 5. E. coli diarrheas 6. Others: Ulcers, Camplyobacteriosis, Listeriosis, Brucellosis, and more. Foodborne and Waterborne Intoxications Enterotoxin causes cramps, diarrhea and vomiting. Bacillus cerus food poisoning Bacillus cereus Enterotoxin causes cramps, abdomian pain and watery diarrhea Clostridium food poisoning Clostrium perfringens Enterotoxin causes cramps, nausea, vomiting and diarrhea. Staphylococcal food poisoning Staphylococcus aureus Exotoxin causes paralysis and respiratory failure. Botulism Clostridium botulinum Characteristics Disease Pathogen Foodborne and Waterborne Infections 1. Typhoid fever 2. Salmonellosis 3. Shigellosis 4. Cholera 5. E. coli diarrheas 6. Others: Ulcers, Camplyobacteriosis, Listeriosis, Brucellosis, and more. Foodborne and Waterborne Infections Exotoxin causes diarrhea and large loss of water and electrolytes; no invasion of tissue. Cholera Vibrio cholerae Shed feces; Shiga toxin; multiply intestinal epithelial cells and spreads; dysentery. Shigellosis Shigella spp. Inhabitants and multiply in intestinal epithelial cells. Can enter bloodstream causing nausea and diarrhea. Salmonellosis Salmonella enterica S. Typhimurium Shed feces; causes high fever,disseminated infection, mortality Typhoid fever Salmonella typhi Characteristics Disease Pathogen • Agent : Salmonella typhi – Gram-negative rod – Acid resistant, high resistance to environmental conditions. • Reservoir: Only humans. Shed in feces. Can remain alive a long time in water, sewage and certain foods. • Transmission: by the five F’s : •f lies, f ood, f ingers, f eces, f omites . Typhoid fever Typhoid fever continued • Incidence typhoid fever (~ ½ Foreign Travel) Fig. 10.6
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2 Typhoid fever continued Symptoms: Incubation period 2 weeks. Bacteria pass through the stomach into the small intestine where they invades the tissue , causing blood invasion, deep ulcers in the intestine and bloody stools. Patient first suffers from high fever (104 ! F) and continual headache. Typhoid (Greek for smoke or clouds in reference to the fever delirium.) Then, fever tends to decline and diarrhea appears (2 nd and 3th weeks). Typhoid fever continued S. typhi multiply in phagocytic cells not in the intestine (unlike salmonellosis). Since it invades the body, the bacteria can be isolated from blood, urine and feces. 1- 5% recovered patients become chronic carriers because they harbor the microbe in their gallbladder and continue to shed bacteria for months.
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This note was uploaded on 05/11/2010 for the course BIOL 1011 taught by Professor Gayda,r during the Spring '08 term at LSU.

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lecture 16 - Lecture 16(Chapter 10 Foodborne and Waterborne...

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