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Unformatted text preview: 1 Lecture 18 Chapter 11 Soilborne and Arthropodborne Diseases A. Soilborne Bacterial Diseases 1. Anthrax 2. Tetanus 3. Gas Gangrene 4. Leptospirosis 5. Melioidosis B. Arthropodborne Bacterial Disease 1. Bubonic Plague 2. Tularemia 3. Lyme Disease 4. Relapsing fever . Soilborne Bacterial Diseases Headaches, muscular aches, fever, kidney failure Leptospirosis Leptospira interrogans Endospores contaminated open wound; toxins destroys adjacent tissue. Gas gangrene Clostridium perfringens Toxin causes uncontrolled muscle contraction. Tetanus Clostridium tetani 3 forms: Cutaneous, Inhalation, Gastrointestinal. Easily septicemic, proliferates in blood. Anthrax Bacillus anthracis Characteristics Disease Pathogen Arthropodborne Bacterial Diseases Relapsing fever (Louse) (TICK) Borrelia recurrentis B. hermsii Spreading gulls-eye rash form initial bite. Heart and nervous symptoms, joint involvements. Lyme disease ( TICK) Borrelia burgdorferi Tularemia (TICK) Francisella tularensis Lymph infection; Large swelling of regional lymph nodes Bubonic plague (FLEA) Yersinia pestis Characteristics Disease Pathogen C. Rickettsial Arthropodborne Diseases Lyme tick Dog tick full (Chapter 11) (Chapter 11) Arthropodborne Bacterial Disease C. Rickettsial Arthropodborne Diseases Rocky Mountain spotted fever Epidemic typhus (typhus fever) Endemic typhus Other rickettsial diseases. Rickettsial Arthropodborne Diseases (A) A fleaborne disease, resembles epidemic typhus, mortality low. Endemic typhus Rickettsia typi A louseborne disease, characterized by high fever, high mortality Epidemic typhus (Typhus fever) Rickettsia prowazekii A tickborne disease, characterized by rash, fever, headache; Rocky Mountain spotted fever Rickettsia rickettsii Characteristics Disease Pathogen 2 Agent: Rickettsia rickettsii very small bacterium that must live inside the cells of its hosts. Rickettsiae live and multiply primarily within cells that line small- to medium-sized blood vessels . Once inside the host the rickettsiae multiply, resulting in damage and death of these cells . Rocky Mountain Spotted Fever Specially stained tick hemolymph cells infected with R. rickettsii ( From CDC web site. ) Rocky Mountain Spotted Fever Reservoir: It is zoonoses . A disease of animals that can be transfer to humans. There are two major vectors of R. rickettsii in the United States, the American dog tick and the Rocky Mountain wood tick. Rickettsiae are transmitted to a vertebrate host through saliva while a tick is feeding . Rocky Mountain Wood Tick Rocky Mountain Spotted Fever It was named Rocky Mountain spotted fever because it was first recognized in 1896 in the Snake River Valley of Idaho It was originally called "black measles" because of the characteristic rash....
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