Electrophilic_Aromatic_Substitution_Reactions

Electrophilic_Aromatic_Substitution_Reactions - M = Fe, Al)...

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Electrophilic Aromatic Substitution Reactions Reaction Electrophile (E + ) Product Source of E + Friedel-Crafts Alkylation R + R 1) R—X X = Cl, Br, OH, etc. 2) Alkene Friedel-Crafts Acylation R C O R C O R O RCO—X (X = Cl, Br, OCOR) Bromination Br Br FeBr 3 Br Br 2 (Catalyst = MX 3 , X = Cl, Br;
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Unformatted text preview: M = Fe, Al) Chlorination Cl Cl FeCl 3 Cl Cl 2 (Catalyst = MX 3 , X = Cl, Br; M = Fe, Al) Iodination I + l I 2 + oxidizing agent (e.g., HNO 3 ) Nitration NO 2 + NO 2 HNO 3 /H 2 SO 4 Sulfonation SO 3 or SO 3 H + SO 3 H Fuming sulfuric acid (H 2 SO 4 /SO 3 )...
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This note was uploaded on 05/13/2010 for the course CHEM ORGANIC CH taught by Professor Dotsevisogah during the Spring '09 term at Cornell University (Engineering School).

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