Unformatted text preview: Alcohols to Aldehydes: Collins Reagent R OH Na 2 Cr 2 O 7 aq. H 2 SO 4 R OH O Oxidation of Primary Alcohols to Carboxylic Acids: Cr(VI) reagents in aqueous acid. Can also use permanganate in basic solution. Na 2 Cr 2 O 7 aq. H 2 SO 4 R OH R R O R Oxidation of Secondary Alcohols to Ketones: Using dichromate. Can also use PCC, Collins Reagent; Cr(VI) reagents in aqueous acid or permanganate in basic solution. R OH SOCl 2 R Cl R R Conversion of Alcohols to Halides R OH PX 3 R X R R Conversion of Alcohols to Halides O H 2 C CH 2 R—MgBr + then H 3 O + R—CH 2C H 2 OH Addition of Organomettalic Reagents to Epoxides H 3 O + R—MgBr R—H Protonolysis of Grignard Reagents...
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- Spring '09
- Carboxylic acid, Grignard Reagents, primary alcohols, Organomettalic Reagents, RCOOH Oxidizing