Genetics 3_Student_handout

Genetics 3_Student_handout - LECTURE 17. GENETICS 3 BEYOND...

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LECTURE 17. GENETICS 3 Wednesday, Feb. 24 BEYOND MENDEL Chromosomal theory of inheritance - molecular basis for dominance and recessivness - meiosis and Mendel's laws of segregation and independent assortment Genes on chromosomes - the white eye mutation in Drosophila and discovery of sex chromosomes - Morgan's experiments with sex-linked inheritance in Drosophila When genes do not assort independently: linkage - physical basis for linkage - recognizing linked genes using a test cross - using frequency of recombination of linked genes to map chromosomes More extensions of Mendel - incomplete dominance - co-dominance, multiple alleles, and human blood groups - interactions among genes and unexpected phenotypes Pedigree analysis - determining patterns of inheritance without doing experiments Looking ahead to evolution: why sex? - cost of sex - role of a variable environment - purging harmful mutations
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2/23/10 1 Mutant, white eye male wild type red eye female All progeny, male
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Genetics 3_Student_handout - LECTURE 17. GENETICS 3 BEYOND...

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