overhead3rr_607 AUG-08

overhead3rr_607 AUG-08 - 3. BIOLOGICAL BASIS OF...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
3. BIOLOGICAL BASIS OF PSYCHOACTIVE DRUG USE: PART II 3.1 Receptors Genes and Proteins Dopamine ‘D2’ receptors Relation to schizophrenia and addiction Individual differences in perceived ‘high’ Up-regulation/down-regulation, super-sensitivity Treatment effects and side effects of anti-psychotic medications Down-regulation of D2 receptors, and ‘positive’symptoms Down-regulation and ‘tardive dyskinesia’ 3.2 Acute effects of psychoactive drugs Direction of Action: Agonists vs. Antagonists Agonist = a drug that acts to increase the natural effects of a neurotransmitter Antagonist = a drug that acts to decrease the natural effects of a neurotransmitter 1
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Mechanisms of Action: Direct vs. Indirect If a drug (either agonist or antagonist) exerts its effect by binding to the receptors for a neurotransmitter, it is described as having a “direct” mechanism of action. If a drug (either agonist or antagonist) exerts its effect by
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 05/16/2010 for the course PSY psy607 taught by Professor Martinzack during the Summer '09 term at Ryerson.

Page1 / 6

overhead3rr_607 AUG-08 - 3. BIOLOGICAL BASIS OF...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online