GENETICS_quiz7 - a synonymonous mutation b missense...

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GENETICS (BIO 325) Fall 2009 Quiz 7 for discussion session Name_________________________________________Date________Unique#______ Write unique # you registered 51220 F 8-9a 51225 F 9-10a 51230 W 11-12p 51235 W 12-1p 7 questions + 3 bonus point = 10 total /2 = total 5 points. 1. The codon for one amino acid is changed into a tranlstion-termination (stop) codon. a. synonymonous mutation b. missense mutation c. nonsense mutation d. frameshift mutation 2. a type of nucleotide-pair substitusion in which a pyrimidine replaces a purine or vice versa – for example, G- C to T-A. a. translation b. transition c. transversion 3. Luria and Delbr ü ck fluctuation test used in microbes to establish their random nature of mutation or to measure mutation rates. a. true b. false 4. what is the result of Indel mutation (insertions or deletions of one or more base pairs)?
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Unformatted text preview: a. synonymonous mutation b. missense mutation c. nonsense mutation d. frameshift mutation 5. In whole-genome shotgun assemble, the DNA sequences corresponding to both ends of a genomic DNA insert in a recombinant clone. It can be used to join two sequence contigs into a single ordered and oriented scaffold. a. consensus sequence b. genomic library c. pair-end reads d. physical map 6. The sequencing of a set of clones, such as a minimum tiling path, that corresponds to a genomic segment, a chromosome, or a genome. (Map first, sequencing later) a. whole-genome shotgun sequencing b . ordered-clone sequencing 7. DNA damage occurring in the absence of exposure to mutagens result from depurination and deamination is _____. a. tautomeric shift b. Indel mutations c. spontaneous lesions...
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