Disc 2 - Previous Lecture: Summary/re-cap 1. Lichens is not...

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Previous Lecture: Summary/re-cap 1. Lichens is not the best example for Mutualism-it is more apt to call it “Parasiticism”. Why? Because the Fungus does invade the space of the algae--So use other examples to describe Mutualism 2. Difference between Resistance to phagocytosis and Ability to survive within phagocytes-These ARE different virulence factors 3. Fomites: are inanimate objects that carry microbes/pathogens and transfer them from one individual to another –does not support reproduction
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Mode of transmission: airborne, contact and vehicle AIRBORNE: pathogen is suspended in the air-air is not a suitable medium for growth of the pathogen Droplets-large and small + Dust (a pathogen could adhere to dust particles) Size of the particle matters in that larger the droplet more pathogens are present. But if it is highly infectious, like in TB, even microdroplets are sufficient to cause infection CONTACT: coming together of source or reservoir of the pathogen and the host-
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Contact can be Direct or indirect Direct: 1)person-person, 2) vertical contact-mother to child 3) Airborne droplets (<1meter-therefore droplet transmission depends on proximity of source and host, example: Influenza) Indirect: Transmission of the pathogen from the source to the host through an intermediary-most often an inanimate object. Ex: thermometer, eating utensils etc. (Also considered vehicle transmission) VEHICLE: 1. Fomites 2. Food, water 3. Droplet Nuclei
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microbes is sufficient to cause infection-they get into the alveoli) VECTOR: 1. External: flies carrying shigella-fecal-oral route 2. Internal: rat flea carries Y pestis-rat to human-plague (External and Internal refer to where the pathogen is present) Facultative intracellular pathogens: are those organisms that can reside within the cells of the host or in the environment--These can also be grown in pure culture without host cell support. Ex: M tuberculosis
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Disc 2 - Previous Lecture: Summary/re-cap 1. Lichens is not...

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