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Unformatted text preview: and on lipid bilayer. 1960s: Electron microscopy extensively applied to cell ultrastucture. 1960s: Alec Bangham Father of the liposome. Karp, Fig. 4.9 Singer & Nicholson (1970): Conceptual breakthrough. Proposed fluid mosaic model of membrane structure. Membrane is dynamic, with lipids and other macromolecules more or less free to move laterally within the plane of the lipid bilayer. Transient interactions are possible. 1980s: Concept of lipid rafts defined as microdomains of unique lipids & proteins in outer leaflet of plasma membrane. Karp, Fig. 4.23 (AFM)...
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- Spring '09
- Animal Cell