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bis_104_pq_1_ans_ss_i_2009 - They grow rapidly(2 hour...

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BIS 104 PQ 1 ANS SS I 2009 1. What specific features of S. cerevisiae (budding yeast) make it a useful cell model system for the study of fundamental cellular activities such as cell division and protein trafficking? Both the budding yeast, S. cerevisiae and the fission yeast, S. pombe have a number of properties that make them amenable to cell and molecular biology studies. They are the simplest of the eukaryotic cells, having a relatively small genome and small number of chromosomes compared to mammalian cells.
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Unformatted text preview: They grow rapidly (2 hour doubling time) on simple defined nutrient media, are easily mutagenized and thus are ideal for genetic and molecular studies. Moreover, they can be grown in the haploid state so that single gene mutation studies are more easily performed. Although relatively simple cells, they have and express many of the important genes that control basic cell functions found in cells from more “advanced” organisms, such as mouse and human....
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