Handout%2019 - BIPN 102 Spring 2010 Ni Mo Week 2: Handout...

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BIPN 102 – Spring 2010 Ni Mo Week 2: Handout #1 nmo@ucsd.edu Material Covered: Lectures 1, 2, 3 OH: Friday 10-11am PC East Conducting and Respiratory Zone Conducting Zone Respiratory Zone What does it contain? Nasal cavity, oral cavity, pharynx, larynx, epiglottis, trachea Respiratory bronchiole, alveoli Gas exchange happening? Size of cross-sectional area? As you move down the respiratory tract, what happens to: - Diameter of tubes? - Conduction velocity? - Resistance? Alveoli/Surfactant Alveoli are constantly under pressure and will be on the verge of collapse if we start hyperventilating. What can prevent this from happening? Surfactants secreted from type II cells. 2 types of cells: - Type I: epithelial cells with minimal thickness to maximize gas exchange - Type II: secretes lung surfactants. No gas exchange. o Surfactants – Main component: _______________ Function: ___ surface tension of alveoli, which will ___ compliance, and therefore prevent alveolar collapse. Bronchioles  Bronchioles can dilate or constrict depending on various molecular mechanisms. What are some of these regulation factors? 1. Bronchodilation - 2. Bronchoconstriction - - - Propranolol is a non-selective β -blocker intended as an anti-hypertensive and anti-arrhythmic drug. A patient with tachycardia and a history of asthma took propranolol to treat his rapid heart rate. After taking a therapeutic dose, his heart rate returned to normal. However, he experienced
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Handout%2019 - BIPN 102 Spring 2010 Ni Mo Week 2: Handout...

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