BIPN 144-lec5

BIPN 144-lec5 - BIPN 144: Lecture 5 (4/13/10) I. fig 5.1 a....

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BIPN 144: Lecture 5 (4/13/10) I. fig 5.1 a. intrinsic: germline factors/maternal factors i. frog: separate egg into two compartments ii. flies: DORSAL b. extrinsic factor: point of sperm entry (frog) i. sperm constrained to enter in equator of egg (mesoderm) and this entry defines the ventral pole of the embryo ii. cortical rotation: factors move to the dorsal face (only active during rotation) before rotation: latent dorsalizing factors; after: active dorsalizing factors 1. transcription factor: β -catenin (low @ ventral and high at dorsal) most important in the mesoderm layer, but it is all over the embryo a. helps partition the mesoderm into zones i. most dorsal : spemann organizer : 1. forms a tissue called notochord a. backbone 2. the Spemann organizer induces the cells next to it, in the animal to make neuralectoderm with nural inducing signals. ii. Middle: muscle and heart iii. Ventral: blood b. Neuralectoderm iii. for export only signaling
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1. VegT:activates expression of mesoderm inducing
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BIPN 144-lec5 - BIPN 144: Lecture 5 (4/13/10) I. fig 5.1 a....

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