7MembranesWAPDF

7MembranesWAPDF - Key Concepts Covered by Exams Membrane...

Info iconThis preview shows pages 1–11. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Key Concepts Covered by Exams Membrane structure and function Principal structure and function of biological membranes Fluid-mosaic model of a membrane and experimental evidence for it Factors affecting membrane fluidity in various organisms Be able to relate saturated and unsaturated fats to the ecology of organisms Understand the principles of the passage of hydrophilic (polar) and hydrophobic (nonpolar) molecules through biological membranes and be able to apply these to examples from lecture Membrane proteins: understand when transport proteins are needed and when ATP energy is needed for the transport of substances ATP-fueled ion pumps (K + /Na + pump and H + pump) Co-transporters (Na +-glucose and H +-sucrose) and their coupling with ion pumps Understand the genetic and dietary factors affecting LDL levels, the LDL receptor, and plaque formation and be able to relate this to heart disease Principal difference in signal transduction of a protein hormone versus a steroid hormone Functions of Membranes • Regulate movement of substances in and out of cells or organelles • Allow maintenance of stable internal environment within cells; separate inside space into specialized regions, organelles , for incompatible functions Membrane Structure and Function P hospholipid bilayer- fundamental structure of membrane Phospholipids have hydrophilic & hydrophobic regions. Fig. 7.2 Fluid-Mosaic Membrane Model • Membranes typically “ fluid ” with consistency of salad oil (fluidity level varies with temperature!) • Membranes are mosaic of phospholipids & proteins Phospholipid bilayer Hydrophobic regions of protein Hydrophilic regions of protein Fig. 7.3 Experimental evidence for “mosaic” property of membranes Freeze-fracture membrane and observe protein “bumps” Fig. 7.4 Andrew Staehelin Fig. 7.6 3. Observe migration & mixing of proteins. 2. Fuse cells to form “hybrids”. Experimental evidence for “fluid” property of membranes: 1. Mark proteins on cells with different fluorescent dyes. The effect of unsaturated versus saturated phospholipids on membrane fluidity Particularly important in plants (stationary; no thermoregulation!) & in algae and bacteria Fluid Viscous Unsaturated hydrocarbon tails with kinks Saturated hydro- carbon tails Fig. 7.5 (b) Which type of fatty acid would be more abundant in the membranes of plants, algae, and bacteria in cold environments? A) saturated B) unsaturated Which type of fatty acid would offer the greatest benefit for membranes of plants, algae, and bacteria in the coldest habitats on Earth? A) saturated B) monounsaturated C) polyunsaturated Which type of fatty acid would be more abundant in the membrane phospholipids of plants, algae, and bacteria from hot environments?...
View Full Document

This note was uploaded on 05/19/2010 for the course BIO BIO taught by Professor Johnson during the Fall '10 term at Colorado.

Page1 / 48

7MembranesWAPDF - Key Concepts Covered by Exams Membrane...

This preview shows document pages 1 - 11. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online