Notes 10-17-08

Notes 10-17-08 - strand, all forms and shapes) capsid...

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Post transcription events-microRNA (miRNA), silencing RNA (siRNA) miRNA-undergo similar transcription events, yet have special structures, with complimentary regions -small single stranded RNA molecules which can degrade mRNA or block its translation -hairpin structures -composed of a series of proteins which assist in processing microRNA into mRNA; help create the hairpin structure (connected by hydrogen bonds) -protein called a dicer comes and binds to the microRNA, sits at the top of the microRNA and cuts the top of it off miRNA protein binds to the mRNA to create the miRNA protein complex post translational events-protein folding and denaturation ubiquitinated mediated degradation by boxes called proteasomes (recognize the ubiquinated proteins which need to be degraded) viruses require a host for replication made of two specific elements: genome of nucleic acid (DNA, RNA, double or single
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Unformatted text preview: strand, all forms and shapes) capsid protein coat-made of coat proteins, so that virus can put DNA inside of it 1) attach to the host cell 2) deliver its genome 3) replicate its genome (use the replication enzymes of the host) 4) synthesize capsid genome (use the hosts ATP) 5) package the genome to produce new virus 6) infect another host virus infective cycle-life cycle of the virus tools needed for recombinant DNA technology restriction enzymes-proteins which recognize and cleave specific DNA sequences DNA ligase-protein which joins together the separated DNA fragments (forms the phosphodiester bond) Plasmids-small, circular, double stranded DNA molecules which replicate themselves with host enzymes (provides the DNA for the host to use); many copies per cell Origin of replication...
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This note was uploaded on 05/20/2010 for the course BIOL 101 taught by Professor Fevzidaldal during the Fall '08 term at UPenn.

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Notes 10-17-08 - strand, all forms and shapes) capsid...

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