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Notes 10-22-08 - induces the M phase CDK always present MPF...

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Prokaryotes divide by binary division To do so, the cell must 1) become larger and 2)star making an exact copy of its chromosomes; the replication will yield Replication, Elongation, Divide [RED] Eukaryotes Organelles replicate separately Mitosis-replication of DNA Cytokinesis-physical separation of the cytoplasm Mitotic phase (mitosis and cytokinesis) Interphase (everything else) -3 subphases (G1, S <DNA synthesis>, G2) -3 control points (G1, G2, M) Cell Cycle Regulation -cyclin protein -CDK protein (cyclin dependant kinase) cyclin + CDK make a protein complex called MPF (Maturation Promoting Factor)
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Unformatted text preview: [ induces the M phase] CDK always present, MPF and cyclin concentration is variable during different phases of the cell cycle MPF breaks down the nuclear membrane by phophorylation of the lamins, causes chromatin to condense into chromosomes, causes spindle structure to form Ends of chromosomes= telomeres Middle of chromosomes = centromere kinetichore movement spindle = set of microtubules attached to the centromeres 5 phases: prophase prometaphase metaphase anaphase telophase/cytokinesis...
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