ch22ppt - Chapter 22 The Lymphatic System Resistance is the...

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22-1 Chapter 22 The Lymphatic System Resistance is the ability to ward off disease lack of resistance is termed susceptibility Nonspecific resistance to disease general defensive mechanisms effective on a wide range of pathogens (disease producing microbes) Specific resistance or immunity is ability to fight a specific pathogen cell-mediated immunity antibody-mediated immunity
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22-2 Lymphatic System Organs, vessels and a fluid called lymph similar to interstitial fluid Organs involved red bone marrow thymus spleen lymph nodes diffuse lymphatic tissue tonsils, adenoids & peyers patches
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22-3 Functions of the Lymphatic System Draining excess interstitial fluid & plasma proteins from tissue spaces Transporting dietary lipids & vitamins from GI tract to the blood Facilitating immune responses recognize microbes or abnormal cells & responding by killing them directly or secreting antibodies that cause their destruction
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22-4 Capillaries that begin as closed-ended tubes found in spaces between cells Combine to form lymphatic vessels resemble veins with thin Fluid flows through lymph nodes towards large veins above the heart lymph emptied into bloodstream
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22-5 Lymphatic Capillaries Found throughout the body except in Avascular tissue (cartilage, epidermis Structure is designed to let tissue fluid in but not out anchoring filaments keep tube from collapsing under outside pressure overlapping endothelial cells open when tissue pressure is high (one-way valve) In GI tract, known as lacteals -- contain chyle
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22-6 Right side head, arm & chest empty into right lymphatic duct and rest of body empties into thoracic duct Lymph is dumped directly into left & right subclavian veins
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22-7 Fluid & proteins escaping from vascular capillaries is collected by lymphatic capillaries & returned to the blood Respiratory & muscular pumps promote flow of lymphatic fluid Lymphatic vessels empty into subclavian veins
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22-8 Widely distributed throughout the body Primary lymphatic organs provide environment for stem cells to divide & mature into B and T lymphocytes red bone marrow gives rise to mature B cells thymus is site where pre-T cells from red marrow mature site where most immune responses occur lymph nodes, spleen & lymphatic nodules
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22-9 Thymus Gland Large organ in infants (70 g) but atrophied as adult (3 g) 2 lobed organ located in mediastinum it into lobules medulla Cortex macrophages Medulla reticular epithelial cells produces thymic hormones Hassall’s corpuscles
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This note was uploaded on 05/23/2010 for the course BIO 222 taught by Professor Brooks during the Spring '10 term at Prairie State College .

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ch22ppt - Chapter 22 The Lymphatic System Resistance is the...

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