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Unformatted text preview: e) What role does cholesterol play in regulating plasma membrane fluidity? (2) At physiological temperatures, cholesterol usually contributes to membrane stability and viscosity. But, it also acts as a buffer against abrupt transition changes between sol and gel states. Cholesterol helps to maintain optimal functional fluidity as environmental parameters change. f) What additional information about the erbB2 protein shown in fig. 2 could be obtained by subjecting the cells to freeze-fracture followed by scanning electron microscopy (SEM)? (2) Freeze-fracture / SEM would reveal the surface topography of the inner faces of both inner and outer bilayer leaflets. It would show the presence, size, and relative distribution of integral membrane proteins. Demo...
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- Spring '08