SC_0808_1up - TUMORS OF THE PLEURA (OTHER THAN DIFFUSE...

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Unformatted text preview: TUMORS OF THE PLEURA (OTHER THAN DIFFUSE MALIGNANT MESOTHELIOMA) Anna Sienko, MD Department of Pathology The Methodist Hospital Houston, Texas EWING’S SARCOMA PRIMITIVE NEURAL ECTODERMAL TUMOR (PNET) DESMOPLASTIC SMALL ROUND CELL TUMOR (DSRCT) EWING’S SARCOMA/PNET ¾ Ewing’s sarcoma is the second most common bone tumor occurring in children and young adults accounting for 10-15% of primary bone tumors and can involve the chest area (ribs 13%) with extension into soft tissues ¾ Extraskeletal Ewing’s sarcoma arises in soft tissue and reported cases of chest/chest wall primaries EWING’S SARCOMA/PNET ¾ Thoracopulmonary primitive neuroectodermal tumor (PNET) or Askin tumor first described in1979 is also “a round small blue cell tumor” occurring in the first 2 decades of life with rare cases reported in older patients (69 yr. male) SMALL ROUND BLUE CELL TUMORS In past Ewing’s/Extraskeletal Ewing’s, peripheral primitive neuroectodermal tumors (PNET) and Askin’s tumor were thought to be different neoplasms SMALL ROUND BLUE CELL TUMORS ¾ Tumors that showed more uniform primitive cells with scant cytoplasm and cytoplasmic glycogen were usually classified as Ewing’s sarcomas ¾ Tumors composed of primitive cells that showed...
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SC_0808_1up - TUMORS OF THE PLEURA (OTHER THAN DIFFUSE...

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