L01-2010 - BioNB2220 Cornell University Spring 2010 Carl D...

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BioNB2220 Spring 2010 Cornell University Carl D. Hopkins Lecture 01. Introduction to Neurobiology Reading Assignment Purves, D., Augustine, G. J., Fitzpatrick, D., Hall, W. C., LaMantia, A.-S., McNamara, J. O., and White, L. E. (2007) Neuroscience . Sinauer Assoc. Sunderland, Mass., Chapter 1 (pp. 1-22). Summary The overall goals of this course are for students to: 1) Demonstrate mastery of the core principles and concepts of the field of Neuroscience -- a multi-disciplinary field that attempts to understand the biological basis of neural activity in behavior. 2) Demonstrate their understanding of the scientific method as applied to neuroscience by linking fundamental concepts and principles in the field to the basic observations and experiments that led to their development. 3) Be conversant in multiple approaches used in the field of Neuroscience from molecules, to cells, and to neural circuits. 4) Demonstrate knowledge and understanding of the importance of biological evolution for the study of the human nervous system. Some specific goals are for students to: demonstrate understanding of how information is encoded by neurons and neural circuits: how perceptions are represented, stored, and recalled for later use in decision making and control of behavior. understand the basic electrical and chemical mechanisms through which neurons communicate with one another. Apply the laws of chemistry and physics to the basic principles of neuronal and synaptic activity and be able to solve problems related to generation of electrical impulses, the function of synapses, the generation of patterned discharges by neural circuits, and the formation of short and long term memories by neural circuits. learn the major components of the central and peripheral nervous system and their functional roles to the extent they are known. understand modern views of how the nervous system is built during development, changes with experience during life, and is disrupted by injury and disease.
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BioNB2220 Spring 2010 Cornell University Carl D. Hopkins Kitten cerebellum from (Ramón y Cajal, 1909) Learning Objectives for Lecture 01 Students should be able to: 1) Explain the neuron doctrine and its importance to the field of Neuroscience. 2) Identify the components of a neuron: soma, dendrite, axon, terminals, axon hillock, node, synapse. 3) Provide an example of a sensory-motor reflex and explain its function. 4) Explain the major events in the evolution of nervous systems. Lecture Outline 1) The nervous system is composed of cells: This is the basis of the Neuron Doctrine, formulated in 1891 by Waldeyer-Hartz (1891) and finally established in 1954 (Shepherd, 1991). There are two basic cell types: neurons (nerve cells) and glia (‘glue’ or supporting cells). We take this for granted today, but prior to 1891 there was no good way to see neurons in their entirety. Most scientists at the
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This note was uploaded on 05/25/2010 for the course BIONB 2220 taught by Professor Hopkins,c.d. during the Spring '10 term at Cornell.

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L01-2010 - BioNB2220 Cornell University Spring 2010 Carl D...

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