L06-2010 - BioNB222 Cornell University Spring 2010 Joseph...

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BioNB222 Spring 2010 Cornell University Joseph Fetcho Lecture 06. Ion Channel Structure and Function Reading Assignment Purves, D. , Augustine, G. J., Fitzpatrick, Hall, W.C. LaMantia, A.-S., McNamara, J.O. and White, L. E. (2008) Neuroscience. Sinauer Associates, Inc. Sunderland, Mass. Chapter 4. Learning Objectives: 1. To learn how single channels underlie the flow of the currents through the neuronal membrane. 2. To examine the molecular and crystal structure of ion channel proteins to understand how they give rise to channel properties such as selectivity, high ion throughput, and voltage sensitivity. 3. To learn about the diversity of ion channels and the importance of that diversity. Lecture Outline We now know much about the physiology and molecular structure of single ion channels. In fact, two relatively recent Nobel prizes have been awarded for studies examining the structure and function of ion channels at the level of individual channels. In this lecture, we will look more closely at the channels and how their properties give rise to the
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This note was uploaded on 05/25/2010 for the course BIONB 2220 taught by Professor Hopkins,c.d. during the Spring '10 term at Cornell University (Engineering School).

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L06-2010 - BioNB222 Cornell University Spring 2010 Joseph...

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