BMI 211 01.21.10

BMI 211 01.21.10 - Effective Design in Clinical Informatics...

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Effective Design in Clinical Informatics BMI 211/CS 271 Amar Das Assistant Professor Medicine (Biomedical Informatics)
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Planned Assignments Assignment Released Due HW #1 1/15 1/22 Mid quarter presentation 2/2 HW #2 2/5 2/12 HW #3 2/19 2/26 End quarter presentation 3/2, 3/4 HW #4 3/5 3/12 Written report 3/19
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Conceptual Modeling Define a set of domain concepts and relationships that are Explicit Consistent Comprehensive Create a central computable domain model for application developers
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‘How to Model’ Principles Specify a sufficiently narrow field of knowledge Declare a set of principles by which knowledge will be modeled Build a structured set of foundational relationships Define coherent segments of knowledge using a modeling formalism/language
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Modeling Time and Process in Systems
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Adjuvant Chemotherapy for Localized Breast Cancer Dose Dense AC followed by Paclitaxel Doxorubicin 60 mg/m2 IV q14 days x 4 cycles Cyclophosphamide 600 mg/m2 IV q14 days x 4 cycles Paclitaxel 175 mg/m2 IV q14 days x 4 cycles day 57 1 day 71 2 day 85 3 day 99 4 day 1 1 1 day 15 2 2 day 29 3 3 day 43 4 4 Ref: Citron ML et al, JCO 21:1431-1439, 2003.
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Modeling Time and Process Temporal Information Guideline Models
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Temporal Information Database TOD Temporal relational model Knowledgebase TNET KBTA
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TOD Model The Time-Oriented Database Goal: Support queries for outpatient clinical research Model: A three-dimensional view of medical data (patient identification, clinical parameter, and date of visit) Forms the basis of temporal models in classic EMR systems
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Temporal Relational Model Temporal extension to relational databases Goal: Provide a method to instantiate arbitrarily complex conditions Model: Interval-based queries over temporal representations Allows temporal querying for decision support applications
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Standard Relational Model Time Drawn Time Entered MRNO WBC Aug 12, 2003 6:50:23AM Aug 12, 2003 9:25:47AM 123-4567 2.5 Aug 13, 2003 7:33:54AM Aug 13, 2003 9:41:12AM 123-4567 2.7
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Standard Relational Model Time Started Duration MRNO Drug Name Drug Dose Aug 4, 2003 12:00AM 7 123-4567 Clozapine 550 Aug 11, 2003 12:00AM 7 123-4567 Clozapine 600
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Standard Relational Model Time Drawn Time Entered MRNO WBC Aug 12, 2003 6:50:23AM Aug 12, 2003 9:25:47AM 123-4567 2.5 Aug 13, 2003 7:33:54AM Aug 13, 2003 9:41:12AM 123-4567 2.7 Time Started Duration MRNO Drug Name Drug Dose Aug 4, 2003 12:00AM 7 123-4567 Clozapine 550 Aug 11, 2003 12:00AM 7 123-4567 Clozapine 600
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Start Time End Time MRNO Drug Name Drug Dose Aug 4, 2003 Aug 10, 2003 123-4567 Clozapine 550 Aug 11, 2003 August 17, 2003 123-4567 Clozapine 600 Start Time End Time MRNO Drug Name Aug 4, 2003 August 17, 2003 123-4567 Clozapine Temporal Relational Model Time Started Duration MRNO Drug Name Drug Dose Aug 4, 2003 12:00AM 7 123-4567 Clozapine 550 Aug 11, 2003 12:00AM 7 123-4567 Clozapine 600
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TNET Model Temporal data management for
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This note was uploaded on 05/26/2010 for the course CS 271 taught by Professor Das during the Winter '10 term at Stanford.

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BMI 211 01.21.10 - Effective Design in Clinical Informatics...

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