CHEM114B_Practice Final_Key

CHEM114B_Practice Final_Key - CHEM 114B Final 2009 Last...

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CHEM 114B Final 2009 Last Name, First Name Student ID and Section Number Page 1 CHEM 114B Final Exam 3:00pm- 5:59pm March 20, 2009 Write your name and student ID on EVERY page of the exam Fill in the bubbles for your student ID on the scantron. 5HSODFH WKH DOSKDEHWLFDO OHWWHU LQ \RXU VWXGHQW ,' ZLWK WKH QXPEHU µ±¶ (e.g., A = 1, U = 1) By signing below, I authorize Dr. Wang to leave my exam out for pick-up outside of Urey Hall 4254. I understand that my exam will be available for public scrutiny, and may be stolen. _______________________________________ Questions 1-50 Multiple Choice _________ out of 150 points Questions 51-60 Short Answer _________ out of 60 points Total _________ out of 210 points
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CHEM 114B Final 2009 Last Name, First Name Student ID and Section Number Page 2 Questions 1-50 (3 pts. each): Multiple choice 1. (3 pts.) In which of the following metabolic co QYHUVLRQV LV $73 ³JHQHUDWHG´ GXULQJ JO\FRO\VLV" A) 1,3-Bisphosphoglycerate o 3-phosphoglycerate B) Glucose o glucose-6-phosphate C) 2-Phosphoglycerate o 3-phosphoglycerate D) Fructose-1,6-bisphosphate o dihydroxyacetone phosphate + glyceraldehyde-3-phosphate E) Glucose-6-phosphate o fructose-6-phosphate Answer: A 2. (3pts.) How many high-energy phosphate bonds are expended in gluconeogenesis of synthesizing one glucose? A) three B) six C) two D) four E) one Answer: B 3. (3pts.) Which of the following is correct concerning the following metabolic reaction? Pyruvate + CO 2 + ATP o oxaloacetate + ADP + P i A) This metabolic reaction is catalyzed by pyruvate carboxykinase. B) The enzyme that catalyzes this reaction is covalently bonded to the coenzyme pyridoxal phosphate. C) This reaction can be considered as part of the pentose phosphate pathway. D) The enzyme that catalyzes this reaction is located in the endoplasmic reticulum of the cell. E) The enzyme that catalyzes this reaction is activated by high concentrations of acetyl-CoA. Answer: E 4. (3pts.) Biosynthesis requires the expenditure of free energy. Which of the following metabolic conversions involved in glucose synthesis requires the direct expenditure of ATP free energy (ATP is also a reactant)? A) Glyceraldehyde-3-phosphate + dihydroxyacetone phosphate o fructose-1,6-bisphosphate B) Fructose-1,6-bisphosphate o fructose-6-phosphate C) 3-Phosphoglycerate o 1,3-bisphosphoglycerate D) 1,3-Bisphosphoglycerate o glyceraldehyde-3-phosphate E) None of the above. Answer: C
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CHEM 114B Final 2009 Last Name, First Name Student ID and Section Number Page 3 5. (3pts.) Avidin, a protein in egg whites, binds biotin very tightly and prevents its absorption in the intestine. Consumption of large amounts of raw eggs can result in a biotin deficiency. Which of the following metabolic conversions cannot occur without biotin? (Note: This is not a problem with cooked eggs because cooking denatures avidin.) A) Oxaloacetate o phosphoenolpyruvate B) 1,3-Bisphosphoglycerate o glyceraldehyde-3-phosphate C) Fructose-1,6-bisphosphate o fructose-6-phosphate D) Pyruvate o oxaloacetate E) Phosphoenolpyruvate o 2-phosphoglycerate Answer: D 6. (3pts.) In skeletal muscle cells, the NADH that is produced by glycolysis under anaerobic conditions (vigorous exercise) is regenerated to NAD +
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This note was uploaded on 05/26/2010 for the course CHEM CHEM 114B taught by Professor Wang during the Winter '10 term at UCSD.

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CHEM114B_Practice Final_Key - CHEM 114B Final 2009 Last...

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