17280457d01 - Neurotransmitters opioids and pain Tabel 24-2...

Info icon This preview shows pages 1–7. Sign up to view the full content.

View Full Document Right Arrow Icon
1 1 Neurotransmitters: opioids and pain Tabel 24-2 Fig. 24-13a 2 Neurotransmitters: opioids and pain Fig. 24-13b
Image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
2 3 Neurotransmitters: opioids and pain Fig. 24-13b 4 Neurotransmitters: opioids and pain 2002: Afghanistan has again established itself as the world's largest opium poppy producer this year, with growers taking advantage of a power vacuum during the U.S.-led war and the collapse of the Taliban regime
Image of page 2
3 5 Internalisation of GPCRs: exception: dopamine D4 receptor No internalization No phosphorylation 6 Internalisation of GPCRs: exception: dopamine D4 receptor No recruitment of beta-arrestin2
Image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
4 7 Internalisation of GPCRs: exception: dopamine D4 receptor Studying receptor internalisation in hippocampal neurons 8
Image of page 4
5 9 Dopamine: introduction Arvid Carlsson Paul Greengard Eric Kandel The Nobel Prize in Physiology or Medicine 2000 10 Dopamine: introduction Arvid Carlsson The Nobel Prize in Physiology or Medicine 2000
Image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
6 11 Dopamine: introduction Arvid Carlsson The Nobel Prize in Physiology or Medicine 2000 12 Dopamine: four neuronal pathways 1. Mesocortical pathway: barb2right Ventral tegmentum to cortex (particularly the frontal lobes) * Cognitive functions * Motivational and emotional response 2. Mesolimbic pathway: barb2right Ventral tegmentum to limbic system (nucleus accumbens, hippocampus,amygdala) * feelings of reward and desire * dopamine is released in these areas by naturally rewarding experiences such as food, sex, certain drugs, etc.) barb2right
Image of page 6
Image of page 7
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern