17280457d01 - Neurotransmitters opioids and pain Tabel 24-2...

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1 1 Neurotransmitters: opioids and pain Tabel 24-2 Fig. 24-13a 2 Neurotransmitters: opioids and pain Fig. 24-13b
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2 3 Neurotransmitters: opioids and pain Fig. 24-13b 4 Neurotransmitters: opioids and pain 2002: Afghanistan has again established itself as the world's largest opium poppy producer this year, with growers taking advantage of a power vacuum during the U.S.-led war and the collapse of the Taliban regime
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3 5 Internalisation of GPCRs: exception: dopamine D4 receptor No internalization No phosphorylation 6 Internalisation of GPCRs: exception: dopamine D4 receptor No recruitment of beta-arrestin2
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4 7 Internalisation of GPCRs: exception: dopamine D4 receptor Studying receptor internalisation in hippocampal neurons 8
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5 9 Dopamine: introduction Arvid Carlsson Paul Greengard Eric Kandel The Nobel Prize in Physiology or Medicine 2000 10 Dopamine: introduction Arvid Carlsson The Nobel Prize in Physiology or Medicine 2000
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6 11 Dopamine: introduction Arvid Carlsson The Nobel Prize in Physiology or Medicine 2000 12 Dopamine: four neuronal pathways 1. Mesocortical pathway: b Ventral tegmentum to cortex (particularly the frontal lobes) * Cognitive functions * Motivational and emotional response 2. Mesolimbic pathway: b Ventral tegmentum to limbic system (nucleus accumbens, hippocampus,amygdala) * feelings of reward and desire * dopamine is released in these areas by naturally rewarding experiences such as food, sex, certain drugs, etc.) b addiction
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This note was uploaded on 05/28/2010 for the course WE CHMOBI0000 taught by Professor Geertvanloo during the Spring '10 term at Ghent University.

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17280457d01 - Neurotransmitters opioids and pain Tabel 24-2...

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