les_6_05112009 - monogenic conditions 13 20 and 27/10...

Info iconThis preview shows pages 1–7. Sign up to view the full content.

View Full Document Right Arrow Icon
monogenic conditions: 13, 20 and 27/10 hereditary cancer syndromes inborn errors of metabolism neurodegenerative diseases connective tissue diseases susceptibility to infectious diseases gene therapy: current possibilities and future perspectives
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
gene therapy genetic modification of host cells in order to reach a therapeutic benefit ex or in vivo somatic or germinal acquired or constitutional diseases viral or non-viral vectors integrating or episomal
Background image of page 2
gene therapy transduction : introduction of a gene in a target cell transgene : the transduced gene tropism : spectrum cell types that can be transduced by a virus
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
the ideal vector easy production efficient transduction (dividing and quiescent cells) sustained expression immunologically inert tissue specific targetting adequate capacity
Background image of page 4
vectors for gene therapy
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
diseases for gene therapy ‘simple’ ‘complicated’ inheritance recessive dominant gene defect
Background image of page 6
Image of page 7
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 05/28/2010 for the course WE BIBI000000 taught by Professor Johangrooten during the Spring '10 term at Ghent University.

Page1 / 15

les_6_05112009 - monogenic conditions 13 20 and 27/10...

This preview shows document pages 1 - 7. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online