CH4handoutsdiagnostics

CH4handoutsdiagnostics - Use of diagnostic tests Use of...

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1 MPET- Diagnostics Use of diagnostic tests Diagnosis in the strict sense Follow-up Screening Treatment MPET- Diagnostics Use of diagnostic tests Diagnosis in the strict sense = in a patient with a certain pattern of signs and symptoms derived from anamnesis (= disease history obtained by questioning) and clinical examination Which disease ? Which subtype ? Which degree ? MPET- Diagnostics Use of diagnostic tests Follow-up Assess the effect of a treatment Monitoring : feedback to treatment (quantitative) e.g # drug levels # side effects chemotherapeutic agents # insulin treatment MPET- Diagnostics Use of diagnostic tests Screening = in non-symptomatic individuals, no indication for the disease + population + high risk groups + patients : pre-operative AIM = early diagnosis (before complaints, symptoms, signs) + better prognosis : e.g. cervix carcinoma + public health : tuberculosis MPET- Diagnostics Use of diagnostic tests Treatment + blood groups + HLA (transplantation) + renal function + pharmacogenetics MPET- Diagnostics Use of diagnostic tests v Determine medical management (in the broad sentence : also way of living) v Research v Psychology : + doctor + patient
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2 MPET- Diagnostics HEALTH ECONOMICS v Cost/benefit + financial + risks : e.g. biopt + (screening) : over treatment v GOLDEN RULE : « Will the result of the test determine or influence the medical management, the prognosis ? » KINDS OF DIAGNOSTIC TESTS v Immunological v Biochemical v Medical imaging v Histological : immunohistological, in situ hybridisation v Physical : ECG v Invasive
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This note was uploaded on 05/28/2010 for the course WE BIBI000000 taught by Professor Johangrooten during the Spring '10 term at Ghent University.

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CH4handoutsdiagnostics - Use of diagnostic tests Use of...

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