The Golgi network consists of a stack of vesicular tubules

The Golgi network consists of a stack of vesicular tubules...

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The Golgi network consists of a stack of vesicular tubules The Golgi apparatus(GA) consists of a system of membrane enclosed compartments(A). The GA is a stack of compartments with 4-6 cisternae (however, some flagelates contain up to 60). In animal cells the cisternaeare connected by tubules and are found near the nucleus (B). The GA has two distinct faces the cis Golgi-network(CGN) and the trans Golgi- network(TGN). CGN is the entry siteof the GA, TGN the exit site. Oligosaccharid side chains are processed in the Golgi Electron microscopy of theGolgi apparatus (A- unstained)revealing compartmentalization. (B) Staining with osmium, which is preferentially reduced in the cis-
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Unformatted text preview: cisterna. (C) Nucleoside diphosphataseis located in th trans-cisterna, whereas(D) acid hydrolaseis found in the trans-Golgi network. 1 Oligosaccharid side chains are processed in the Golgi Oligosaccharide chains are processed within the lumen of the GA. It appears that the proteins experience different glycosylations and modifications in specific cisternae of the golgi stack (B). Each step is catalyzed by a specific glycosyltransferases. These glycosyltransferases are single pass transmembrane proteins. All enzymes are coupled to the membrane of the cisternae, which is a major difference to the ER processing enzymes. 2...
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This note was uploaded on 05/30/2010 for the course MEDICEN 2100 taught by Professor Saba during the Spring '10 term at Columbia State Community College.

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The Golgi network consists of a stack of vesicular tubules...

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