Lecture3 - Lecture 3 4/6/10 MEMBRANES Background reading:...

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Lecture 3 4/6/10 MEMBRANES Background reading: 5 th edition text: Chapter 10, Pages 629-635, 642-648 4 th edition text: Chapter 10, Pages 593-601, 608-612 Outline: Membranes (continued) Fluid Mosaic Model of membrane structure Membrane proteins Synthetic bilayers Reconstitution of membranes Asymmetry of membranes Membrane fluidity Membrane fusion Transport of small molecules across membranes
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Fluid Mosaic Model of Membrane Structure Singer and Nicolson introduced this present day model in the 1970’s. Proteins float like iceburgs in a sea of lipids. This model pertains to all cell membranes, despite the great diversity of proteins and lipids in them.
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Membrane Proteins α helix Integral membrane proteins: Proteins that span the membrane: Extend across membrane as α -helix of 20 – 30 amino acid residues Extend across membrane as a rolled-up β -sheet. Each strand in the barrel must be at least about 10 amino acids
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Some intrinsic membrane proteins are exposed at only one side of the membrane. NH
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This note was uploaded on 05/30/2010 for the course BIS BIS 104 taught by Professor Privalsky during the Spring '09 term at UC Davis.

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Lecture3 - Lecture 3 4/6/10 MEMBRANES Background reading:...

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