mol1 - BIMM 100 Molecular Biology Lorraine Pillus Professor...

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BIMM 100 Molecular Biology Lorraine Pillus Professor of Molecular Biology Spring 2010 Peterson 108 Please note the frst Few slides oF lecture will be taken From the Syllabus, so are not printed here
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Lecture 1 Summary Nucleotide, nucleic acid components RNA vs DNA Physical properties, structure Denaturation, renaturation Topolgy: supercoiling, topoisomerases RNA structure Class Overview and Syllabus Transcription:overview Prokaryotic vs. eukaryotic
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DNA RNA PROTEIN the central dogma transcription translation (HIV) (polio)
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pentose nucleotide structure
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distinguishing RNA and DNA: the pentoses RNA DNA RNA less stable - the 2 ʼ OH can suffer base-catalyzed hydrolysis to yield 2 ʼ and 3 ʼ monophosphates (see Fig 4-6)
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the bases DNA RNA
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nucleoside sugar + base nucleotide sugar + base + phosphate mono (dAMP), di (dADP), tri (dATP) Naming the Parts ATP GTP energy, signaling
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MBC 4-2 sequence: 5’ C A G 3’ Subunits form polymers via condensation reactions
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DNA structure -- Chagraff’s Rules 1. Base composition varies between species 2. DNA from different tissues of same species has the same composition
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This note was uploaded on 06/03/2010 for the course BIMM Pillus taught by Professor Molecularbiology during the Spring '10 term at UCSD.

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mol1 - BIMM 100 Molecular Biology Lorraine Pillus Professor...

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