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mol2 - BIMM100 Lecture 2 Key Molecular Processes I A Big...

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BIMM100 - Lecture 2 30 Mar MCB 111-126 1 April MCB 126-(139) A Big Day of RNA Key Molecular Processes I (text on [email protected]) FAQs next slide Saving paper? Slides 7-12; 14-19 carry over from Lecture 1 (modified order) DNA Supercoiling -- how it happens Alberts 6-20 From Lecture 1: Supercoils ‘build up’ during processes such as replication and transcription. Would ultimately cause problems if not ‘resolved.’ TOPOISOMERASES are the enzymes that provide resolution. BIMM100 - Lecture 2 30 Mar MCB 111-126 1 April MCB 126-(139) A Big Day of RNA Key Molecular Processes: Check WebCT for info FAQs Sections next week Sections & OH start next week Q. Where does my section meet? Q. Who is my TA? Check WebCT for info Lecture 2 Summary – Key Molecular Processes I Transcription and Translation 3 types of RNA Transcription overview Organization: Bacteria vs. Eukaryotes The Enzyme: RNA polymerase The Process: 3 steps initiation –> elongation –> termination The Product: processing mRNA Translation overview The Code Decoding decoders: tRNAs amino-acyl synthetases Ribosomes and rRNA
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Key Molecular Processes I Transcription ! Translation mRNAs - coding tRNAs - decoding rRNAs - translating mRNA tRNA rRNA structure decoding specificity synthetases structure + function in ribosomes two big days of RNA transcribed from DNA processed in nucleus decoded in cytoplasm translation (transcribed from DNA processed in nucleus) ( transcribed from DNA processed in nucleus) 5 ʼ 3 ʼ 5 ʼ Transcription - overview
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