hcv - HepatitisC V irus Multiplication m ediated TOSIS...

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mediated TOSIS Hepatitis C Virus Multiplication release F|GURt3'sChemar|(dia9'.mo'thcheP.t|t|5cv|rusmU|tipt|(.iionGyc|. .EnvelopedHcvvirionp6rtlc|e5aledep|ctedas'pher5.Fol|owingentro$proba mediatedendocyto5i5'Uncoatingle'u|cintherelea5e that dkects cap-independe some svuctural (core C, El, template for RNA replicatlon in association with intra€ellLrlar membranes catalyzed by viral RNA'dependent RNA polymerase (NS58). Other components ofthe HCV replication comp|exinc|udebothvjta|plote|nsandce||uIa'factor5'Thecomp|ementarm|nu9senseRNAploducthen thleetUnction':mRNA{ol|lans|al'on,remp|ateforRNArep|ication,orprogeny9enometh.lUndergoe5encap5idationintonewv|on pe,mission. 9Uqu4 i.Sita.Clt ",. (2ooo) cvTopuAsM Cellular Receptor NC ,, +ssRNA genome = mRNA CAP-- t' I translation Y polyprotein precursor protease pol hellcase I f autoRroteolysis + Viral enzymes I I Y o ssRNA s' cD81 SR-81 autoproteotViy' translatio2,T Structural proteins pU 5' mRNA 3' 3' o ssRNA s' \ cAP \, {c/c/oI /
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hcv - HepatitisC V irus Multiplication m ediated TOSIS...

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