Lecture13bio - Clicker Question: Which of these mutations...

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BIOLOGY 1001 Friday, February 29, 2008 Lecture 13 Clicker Question: Which of the following does not participate DIRECTLY in translation? Answer: DNA Mutation Change in the sequence of bases in DNA Some common mutations include: Point Mutation – happens when you get a change in one base pair. Insertion Mutation Deletion Mutation Frameshift Mutations: Change amino acid sequence Insertion-Extra base added to the gene Deletion-Base removed from the gene THEFATCATATETHERAT (THE FAT CAT ATE THE RAT) HEFATCATATETHERAT (HEF ATC ATA TET HER AT) Frameshift mutations change every codon past the point of the mutation. This is why Frameshift mutations are almost always BAD! How are mutations involved in evolution? Raw material Most Mutations = Neutral or Harmful Few Mutations = Advantage to individual
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Unformatted text preview: Clicker Question: Which of these mutations is most likely to have a catastrophic effect on the functioning of a protein? Original mRNA AUU GAC UAC Answer: UAU UGA CUA C How Are Genes Regulated? Homeotic Genes shape bodies Gene Regulation Transcription Translation: lifespan of mRNA Modification of proteins Degradation of proteins Figure 10-8 Regulate Transcription: Not all Genes are Turned On Turn on/off individual genes Regulatory proteins Condense regions of chromosomes Condense entire chromosomes Barr bodies = X Chromosome X-Chromosome Inactivation 1 X chromosome inactivated in each cell in female mammals. Which X is different from cell-to-cell...
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This note was uploaded on 06/09/2010 for the course BIOL 1001 taught by Professor Minor during the Spring '08 term at LSU.

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Lecture13bio - Clicker Question: Which of these mutations...

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