St_Johns_Wort - Dietary Supplements St. Johns Wort...

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Dietary Supplements St. John’s Wort Background St. John’s Wort ( Hypericum perforatum ) has been getting a great deal of attention lately due to its use in Europe to treat depression. It is licensed in Germany for the treatment of anxiety, depression, and sleep disorders, with more than 2.7 million prescriptions written for it in 1993 (the seventh most popular preparation in Germany) [1]. St John’s Wort has many different components that have physiological effects, including naphthodianthroms, flavonoids, xanthose, and bioflavonoids [2]. These have different functions and come in different quantities in different preparations. Most preparations report the Hypericum content and this may not be the only active component of interest. Therefore, the typical dose of 2 to 4 g of herb, equating this with 0.2 to 1.0 mg of total hypericin, could be less important. Purported health effects Anti-depressant, treatment of anxiety One of the biggest problems with the use of St. John’s Wort to treat depression is its interaction with other antidepressants and dosages required. The main effect of the active compounds in H. perforatum may be to inhibit the reuptake of serotonin [1]. It may also work by inhibiting monoamine oxidases (quercitrin content) [2].
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St_Johns_Wort - Dietary Supplements St. Johns Wort...

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