Ch. 8- Bacterial Genetics

Ch. 8- Bacterial Genetics - Chapter 8 Bacterial Genetics 1...

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Chapter 8 Bacterial Genetics 1
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Mutants 2
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Genetic Changes in Bacteria Mutation Change in DNA sequence (genotype) passed to daughter cells Vertical gene transfer Gene transfer Acquisition of genes from another organism Horizontal gene transfer 3
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Cause of Bacterial Mutations Spontaneous Base substitution Remove or add nucleotides Transposable elements Induced Chemical mutagens Transposons radiation 4
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Spontaneous Mistake in DNA synthesis Base substitution Point mutation (one nucleotide) Silent mutation Missense mutation Nonsense mutation Knockout mutation 5
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Figure 8.3 Types of base substitutions 6
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Spontaneous Mistake in DNA synthesis Removal or addition of nucleotides Three nucleotides added/removed What would happen? One or two nucleotides added/removed Frameshift mutation Shift in reading frame of codons Stop codon may be created 7
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Figure 8.4 Frameshift mutation 8
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This note was uploaded on 06/11/2010 for the course MIBO 2500 taught by Professor Walker during the Spring '08 term at University of Georgia Athens.

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Ch. 8- Bacterial Genetics - Chapter 8 Bacterial Genetics 1...

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