Handout 7 - Histones

Handout 7 - Histones - MCB252CellBiology,Spring2008 Genes...

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MCB 252 Cell Biology, Spring 2008 Handout 07 • DNA  Gene • Gene RNA Regulatory promoter • Regulatory    promoter -500 core promoter • Core promoter +50 -40 Matrix attachment region (MAR) MAR • MARS Boundary element Boundary element • Boundary   element Locus control region (LCR) • LCR Enhancer • Enhancer -4000 • Genes Model of a typical gene
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MCB 252 Cell Biology, Spring 2008 Handout 07 • Regulation of transcription: Chromatin organization. .. In eukaryotes, DNA is assembled into chromatin. • How chromatin is structured and organized within the nucleus. • How Chromatin’s structural integrity is regulated by remodeling enzymes during gene activation and repression. Thus, to understand how transcription is modulating, we need to study:
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MCB 252 Cell Biology, Spring 2008 Handout 07 • Regulation of transcription: Chromatin organization. ..
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Handout 07 • Regulation of transcription: Chromatin organization. .. (H2A, H2B, H3, H4)X2
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Handout 7 - Histones - MCB252CellBiology,Spring2008 Genes...

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