Handout 1 - MCB 252 Cells & Tissues Fall 2009 Handout 2 I....

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Handout 2 I. The Cellular Periphery and Its Role in Controlling Gene Expression a. Physiology of the Plasma Membrane a. Carriers and channels of the plasma membrane b. Cell surface receptors c. Reception and Integration of signals I d. Reception and Integration of signals II I. Transcriptional Control of Gene Expression II. Translational Control of Gene Expression
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Handout 2
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Handout 2 How is a signal received and transmitted by a cell? I. a. Physiology of the Plasma Membrane
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Handout 2 I. a. Physiology of the Plasma Membrane Phospholipids are amphipathic or amphiphillic
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Handout 2
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Handout 2 1. Specific lipid components of the membrane are distributed asymmetrically between the two leaflets of membranes: flip- flop mechanism I. a. Physiology of the Plasma Membrane (Exoplasmic leaflet) (Cytosolic leaflet) 2. Phospatidylserine and apoptosis
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Handout 2 I. a. Physiology of the Plasma Membrane Fluidity Fluidity of the lipid bilayer depends on both its composition and temperature
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Handout 2 Labeling of membrane proteins with a Fluorescent reagent Photobleaching of a small area Fluorescence recovery overtime intensity time (s) F luorescence R ecovery A fter P hotobleaching FRAP Viewed by fluorescence microscopy
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Handout 2 I. a. Physiology of the Plasma Membrane
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Handout 2 • Biomembranes: structure and properties Some membrane proteins are made less mobile by interaction with elements of the cytoskeleton or of the extra-cellular matrix
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Handout 2 Cell can confine proteins and lipids to specific regions of the plasma membrane
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This note was uploaded on 06/12/2010 for the course MCB 252 taught by Professor Prasanth during the Spring '08 term at University of Illinois at Urbana–Champaign.

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Handout 1 - MCB 252 Cells & Tissues Fall 2009 Handout 2 I....

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