BRAE 213-F09 - Class 04 - Tissue Engineering

BRAE 213-F09 - Class 04 - Tissue Engineering - 10/14/2009 1...

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Unformatted text preview: 10/14/2009 1 1 ENGR/BRAE 213 Tissue Engineering 2 Objectives Define tissue and list the four major tissue types Define tissue engineering and describe how engineering is involved Explain what is necessary for a tissue to be engineered Provide examples of tissue engineering 3 Tissue Engineering What is going on here? 10/14/2009 2 4 Tissue Engineering Depicts tissue-engineered cartilage in the shape of an ear Polymeric scaffold shaped like an ear Seeded with cow cartilage cells Implanted in mouse for cultivation 5 Define tissue. In-Class Questions 6 Tissue Four primary tissue types: Epithelial Connective Muscle Nerve 10/14/2009 3 7 Tissue These four primary tissue types found in organs provide: Covering Support Movement Control 8 Epithelial Tissue Characterized by number of sheets and shape of cells Single layer Simple M ltil d Multilayered Stratified Squamous Flattened Cuboidal Columnar 9 Epithelial Tissue Free surfaces (outer and inner) Forms protective interfaces throughout body Organized into glands Adapted for secretion 10/14/2009 4 10 Epithelial Tissue Functions Absorption (e.g., small intestine) Secretion (e.g., glands) Transport (e.g., kidney tubules) Excretion (e.g., sweat glands) Protection (e.g., skin) Sensory reception (e.g., taste buds) 11 Connective Tissue Most abundant and widely distributed tissue Loose woven fibers around and between organs Protective capsules around organs Ligaments and tendons 12 Connective Tissue Specialized connective tissues include: Blood Bone Cartilage Adipose tissue 10/14/2009 5 13 Muscle Tissue Muscles comprise 40 to 50% of body weight Generate forces by contraction Three muscle types Skeletal Smooth Cardiac 14 Muscle Tissue Skeletal muscle Attached to bone via tendons Responsible for locomotion Under voluntary control Smooth muscle Controls size of lumen (vessels, GI tract, etc.) Under involuntary control Cardiac muscle Makes up most of heart mass Under involuntary control 15 Skeletal Muscle Types Slow oxidative Slow twitch fibers ATP produced by aerobic respiration (O 2 present) Endurance activities Fast oxidative Intermediate twitch fibers Intermediate twitch fibers ATP produced normally by aerobic respiration but can switch to anaerobic (O 2 not present, glycolysis) Activities of moderate duration and strength Glycolytic Fast twitch fibers ATP produced anaerobically High strength, short duration activities 10/14/2009...
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This note was uploaded on 06/16/2010 for the course BRAE 213 taught by Professor Hazelwood during the Fall '08 term at Cal Poly.

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BRAE 213-F09 - Class 04 - Tissue Engineering - 10/14/2009 1...

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